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by Lizundia, Regina; Picado, Albert; Cordero, Marlen; Calderon, Alejandra; Deborggraeve, Stijn; Montenegro, Victor M.; Urbina, Andrea
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This article is from Tropical Parasitology , volume 4 . Abstract Introduction:: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs. Materials and Methods:: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica. Results:: T. cruzi-Detect performed well as screening...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166795
PubMed Central
by Emami, Shahram; Hamishehkar, Hadi; Mahmoodpoor, Ata; Mashayekhi, Simin; Asgharian, Parina
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This article is from Journal of Research in Pharmacy Practice , volume 1 . Abstract Enteral feeding tube is employed for feeding of critically ill patients who are unable to eat. In the cases of oral medication administration to enterally fed patients, some potential errors could happen. We report a 53-year-old man who was admitted to intensive care unit (ICU) of a teaching hospital due to the post-CPR hypoxemic encephalopathy. The patient was intubated and underwent mechanical ventilation. A...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076851
PubMed Central
by Mete, Fatih; Kilic, Ertugrul; Somay, Adnan; Yilmaz, Bayram
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This article is from The Indian Journal of Medical Research , volume 135 . Abstract Background & objectives:: Heat stress related hyperthermia may cause damage to various organ systems. There are very few studies on the effects of hyperthermia on the endocrine system. We therefore, investigated effects of exogenously induced hyperthermia on adrenal, testicular and thyroid functions and behavioural alterations in pre-pubertal male Sprague-Dawley rats. Methods:: Three groups of 30-day old...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336856
PubMed Central
by Foote, Christopher
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This article is from BMC Research Notes , volume 7 . Abstract Contributing reviewers: The editors of BMC Research Notes would like to thank all of our reviewers who have contributed to the journal in volume 6 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895785
PubMed Central
by Roncero, Carlos; Vega, Pablo; Martinez-Raga, Jose; Barral, Carmen; Basurte-Villamor, Ignacio; Rodriguez-Cintas, Laia; Mesias, Beatriz; Grau-Lopez, Lara; Casas, Miguel; Szerman, Nestor
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This article is from International Journal of Mental Health Systems , volume 8 . Abstract Background: Since provision of integrated services for patients with dual pathology or dual disorders (coexistence of an addictive disorder and other psychiatric disorders) constitutes an important challenge, this study compared the perceptions of health-care professionals with the existing, current state of specific resources for patients with dual pathology in Spain. Methods: Epidemiological,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158069
PubMed Central
by Sirim, Demet; Widmann, Michael; Wagner, Florian; Pleiss, Jurgen
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This article is from BMC Structural Biology , volume 10 . Abstract Background: Cytochrome P450 monooxygenases (CYPs) form a vast and diverse family of highly variable sequences. They catalyze a wide variety of oxidative reactions and are therefore of great relevance in drug development and biotechnological applications. Despite their differences in sequence and substrate specificity, the structures of CYPs are highly similar. Although being in research focus for years, factors mediating...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224734
PubMed Central
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This article is from United European Gastroenterology Journal , volume 1 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070608
PubMed Central
by Harris, Philippa K
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This article is from BMC Microbiology , volume 13 . Abstract Contributing reviewers: The editors of BMC Microbiology would like to thank all our reviewers who have contributed to the journal in Volume 12 (2012).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576289
PubMed Central
by Guo, Nan; Bindt, Carola; Te Bonle, Marguerite; Appiah-Poku, John; Tomori, Cecilia; Hinz, Rebecca; Barthel, Dana; Schoppen, Stefanie; Feldt, Torsten; Barkmann, Claus; Koffi, Mathurin; Loag, Wibke; Nguah, Samuel Blay; Eberhardt, Kirsten A; Tagbor, Harry; Bass, Judith K; N'Goran, Eliezer; Ehrhardt, Stephan
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This article is from BMC Psychiatry , volume 14 . Abstract Background: There are limited data on the parenting stress (PS) levels in sub-Saharan African mothers and on the association between ante- and postnatal depression and anxiety on PS. Methods: A longitudinal birth cohort of 577 women from Ghana and Côte d’Ivoire was followed from the 3rd trimester in pregnancy to 2 years postpartum between 2010 and 2013. Depression and anxiety were assessed by the Patient Health Questionnaire...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048600
PubMed Central
by Arslan, Zihni; Hermanns, Veronica; Wurm, Reinhild; Wagner, Rolf; Pul, Umit
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This article is from Nucleic Acids Research , volume 42 . Abstract The adaptation against foreign nucleic acids by the CRISPR–Cas system (Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins) depends on the insertion of foreign nucleic acid-derived sequences into the CRISPR array as novel spacers by still unknown mechanism. We identified and characterized in Escherichia coli intermediate states of spacer integration and mapped the integration site at the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081107
PubMed Central
by Giannella-Neto, Daniel; de Brito Gomes, Marilia; Abel, Lucy
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This article is from Diabetology & Metabolic Syndrome , volume 5 . Abstract Contributing reviewers: The Editors of Diabetology and Metabolic Syndrome would like to thank all reviewers, both external and Editorial Board Members, who have contributed to the journal since its inception, and whose valuable support continues to be essential to the success of the journal.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605392
PubMed Central
by Solera, Dafne
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This article is from BMC Cancer , volume 14 . Abstract Contributing reviewers: The editors of BMC Cancer would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909450
PubMed Central
by Chittwar, Sachin; Shivprakash,; Ammini, A. C.
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This article is from Indian Journal of Endocrinology and Metabolism , volume 16 . Abstract Precocious puberty in girls can be due to number of factors of which idiopathic central precocious puberty is the most common etiology. Here, we describe 3 cases of precocious puberty where the first case had premature thelarche in the background history of mother with Type 2 Diabetes Mellitus, cases 2 and 3 had ovarian tumours with heterogeneity in presentation.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603023
PubMed Central
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This article is from Annals of The Royal College of Surgeons of England , volume 94 . Abstract INTRODUCTION: The preliminary results of a pyrocarbon interpositional radiocarpal implant in a small cohort of patients were reviewed. As it is currently only a limited release product, we describe to potential users early complications and negative outcomes. METHODS: Patients were assessed using pain levels, ranges of motion, grip strength, type of and time to return to work as well as pre-operative...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954246
PubMed Central
by Jackson, Chandra L; Kawachi, Ichiro; Redline, Susan; Juon, Hee-Soon; Hu, Frank B
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This article is from BMC Public Health , volume 14 . Abstract Background: Although short sleep is associated with an increased risk of morbidity as well as mortality and has been shown to vary by industry of employment and occupation, little is known about the relationship between work and sleep among Asian Americans. Methods: Using a nationally representative sample of US adults (n = 125,610) in the National Health Interview Survey from 2004–2011, we estimated prevalence ratios for...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057824
PubMed Central
by Scholl, Isabelle; Zill, Jordis M; Harter, Martin; Dirmaier, Jorg
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This article is from Patient preference and adherence , volume 8 . Abstract Background: The concept of patient-centeredness has gained in importance over recent decades, including its growing importance on a health policy level. However, many different definitions and frameworks exist. This renders both research and implementation into clinical practice difficult. This study aimed at assessing how German researchers conceptualize patient-centeredness, how they translate the German equivalent...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155992
PubMed Central
by Pafitis, Natalie
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This article is from BMC Public Health , volume 13 . Abstract Contributing reviewers: The editors of BMC Public Health would like to thank all our reviewers who have contributed to the journal in 2012.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751667
PubMed Central
by Pozo, Oscar J; Marcos, Josep; Fabregat, Andreu; Ventura, Rosa; Casals, Gregori; Aguilera, Paula; Segura, Jordi; To-Figueras, Jordi
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This article is from Orphanet Journal of Rare Diseases , volume 9 . Abstract Background: Acute Intermittent Porphyria (AIP) is a rare disease that results from a deficiency of hydroxymethylbilane synthase, the third enzyme of the heme biosynthetic pathway. AIP carriers are at risk of presenting acute life-threatening neurovisceral attacks. The disease induces overproduction of heme precursors in the liver and long-lasting deregulation of metabolic networks. The clinical history of AIP suggests...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004508
PubMed Central
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This article is from BMC Immunology , volume 14 . Abstract Contributing reviewers: The editors of BMC Immunology would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2012).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622564
PubMed Central
by McGonagle, L; Elamin, S; Wright, DM
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This article is from Annals of The Royal College of Surgeons of England , volume 94 . Abstract INTRODUCTION: Lateral humeral condyle fractures typically require a longer period of internal fixation than other distal humeral fractures due to the increased risk of non-union. K-wires can be buried and left in situ until union or they can be left unburied and require removal after four weeks, with plaster immobilisation until union. There is no consensus as to whether wire burial is preferable or...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954249
PubMed Central
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This article is from PLoS ONE , volume 9 . Abstract Objective: To use direct comparative studies or randomised controlled trials to compare the accuracy of cardiac magnetic resonance (CMR) and single-photon emission computed tomography (SPECT) for the detection of obstructive coronary artery disease (CAD). Materials and Methods: Various databases were searched for original articles published prior to June 2013. Studies were selected that performed both CMR and SPECT in the same or randomised...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919767
PubMed Central
by Sun, Dan; Fan, Xiao-Xing; Yang, Shi-Yao; Zheng, Hong
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This article is from Acta Crystallographica Section E: Structure Reports Online , volume 67 . Abstract In the title compound, C21H30N2O5S, the plane of the dimeth­yl–thio­carbamic group makes a dihedral angle of 78.41 (7)° with the central benzene ring. One of the carbonyl groups in the α,β-unsaturated malonate side chain makes a dihedral angle of 8.73 (10)° with the central benzene ring, while the other carbonyl group makes a dihedral angle of 81.52 (8)°.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151902
PubMed Central
by Ferguson, Lydia; Agoulnik, Alexander I.
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This article is from Frontiers in Endocrinology , volume 4 . Abstract The failure of testicular descent or cryptorchidism is the most common defect in newborn boys. The descent of the testes during development is controlled by insulin-like 3 peptide and steroid hormones produced in testicular Leydig cells, as well as by various genetic and developmental factors. While in some cases the association with genetic abnormalities and environmental causes has been shown, the etiology of cryptorchidism...
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Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602796
PubMed Central
by Morawska, Magdalena
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This article is from BMC Oral Health , volume 14 . Abstract Contributing reviewers: The editors of BMC Oral Health would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921989
PubMed Central
by Leitch, Gordon J; He, Qing
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This article is from Journal of Biomedical Research , volume 25 . Abstract Apicomplexan protozoan parasites of the genus Cryptosporidium infect the gastrointestinal tract and lungs of a wide variety of animals, including humans. The majority of human infections are due to either Cryptosporidiumhominis (C. hominis) and/or Cryptosporidium parvum (C. parvum). The parasite has a complex life cycle that includes both asexual and sexual stages. While there are invasive free living stages,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368497
PubMed Central
by Harold, Simon
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This article is from BMC Plant Biology , volume 14 . Abstract Contributing reviewers: The editors of BMC Plant Biology would like to thank all of our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897928
This article is from Critical Care , volume 18 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070019
PubMed Central
by Katzman, Martin A; Bleau, Pierre; Blier, Pierre; Chokka, Pratap; Kjernisted, Kevin; Van Ameringen, Michael
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This article is from BMC Psychiatry , volume 14 . Abstract Background: Anxiety and related disorders are among the most common mental disorders, with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are under-diagnosed and under-treated. Methods: These guidelines were developed by Canadian experts in anxiety and related disorders through a consensus process. Data on the epidemiology, diagnosis, and treatment (psychological and pharmacological) were obtained...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120194
PubMed Central
by Cornacchia, Catia
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This article is from BMC Pulmonary Medicine , volume 14 . Abstract Contributing reviewers: The editors of BMC Pulmonary Medicine would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923386
PubMed Central
by Hertel, Jana; Bartschat, Sebastian; Wintsche, Axel; Otto, Christian; of the Bioinformatics Computer Lab, The Students; Stadler, Peter F.
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This article is from RNA Biology , volume 9 . Abstract The increase of bodyplan complexity in early bilaterian evolution is correlates with the advent and diversification of microRNAs. These small RNAs guide animal development by regulating temporal transitions in gene expression involved in cell fate choices and transitions between pluripotency and differentiation. One of the two known microRNAs whose origins date back before the bilaterian ancestor is mir-100. In Bilateria, it appears stably...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384580
PubMed Central
by Shao, Emily H.; Karydis, Andreas; Gemenetzi, Maria; Taylor, Simon R.J.
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This article is from Case Reports in Ophthalmology , volume 4 . Abstract Idiopathic orbital inflammatory disease (IOID) is an idiopathic inflammatory process within the orbit that can result in permanent visual impairment. Although high-dose oral corticosteroids are currently the mainstay of therapy, their long-term usage can cause significant toxicity. We present a case of IOID that was successfully treated with the anti-CD20 monoclonal antibody rituximab following failed steroid sparing with...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843906
PubMed Central
by Premendran, S. Jhon; Salwe, Kartik J.; Pathak, Swanand; Brahmane, Ranjana; Manimekalai, K.
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This article is from Journal of Natural Science, Biology, and Medicine , volume 2 . Abstract Background:: To investigate the anti-cobra venom effect of alcoholic extract of Andrographis paniculata. Materials and Methods:: After calculating the LD99 of snake venom, the venom-neutralizing ability of plant extract at the dose 1 g/kg and 2 g/kg was determined using in vitro and in vivo methods. The alleviation in the mean survival time of the animals were used to infer the antivenom property of the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276014
PubMed Central
by Peruzzi, Benedetta; Cutini, Ilaria; Gelli, Anna Maria Grazia; Rondelli, Tommaso; Statello, Marinella; Bencini, Sara; Mannelli, Francesco; Caporale, Roberto; Bosi, Alberto; Fanelli, Alessandra
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This article is from International Medical Case Reports Journal , volume 6 . Abstract Introduction: Pleural effusion as the first clinical manifestation of acute lymphoblastic leukemia (ALL) is a relatively rare event. An early and accurate diagnosis of this clinical picture is very important for adequate patient management. Case presentation: We report the atypical onset of T-lineage ALL in a 31-year-old man. The patient was admitted to the emergency room due to lung failure; at that moment,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818024
PubMed Central
by Carta, Mauro G; Maggiani, Federica; Pilutzu, Laura; Moro, Maria F; Mura, Gioia; Cadoni, Federica; Sancassiani, Federica; Vellante, Marcello; Machado, Sergio; Preti, Antonio
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This article is from Clinical Practice and Epidemiology in Mental Health : CP & EMH , volume 10 . Abstract This study set out to evaluate the effectiveness of a sailing and learning-to-sail rehabilitation protocol in a sample of patients diagnosed with severe mental disorders. The study was a randomized, crossover, waiting-list controlled trial, following recruitment in the Departments of Mental Health of South Sardinia. Participants were outpatients diagnosed with severe mental disorders,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150377
PubMed Central
by Lai, Alvina G.; Denton-Giles, Matthew; Mueller-Roeber, Bernd; Schippers, Jos H. M.; Dijkwel, Paul P.
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This article is from Genome Biology and Evolution , volume 3 . Abstract Genome sequencing of closely related individuals has yielded valuable insights that link genome evolution to phenotypic variations. However, advancement in sequencing technology has also led to an escalation in the number of poor quality–drafted genomes assembled based on reference genomes that can have highly divergent or haplotypic regions. The self-fertilizing nature of Arabidopsis thaliana poses an advantage to...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157834
PubMed Central
by Braconi, Daniela; Bernardini, Giulia; Bianchini, Claretta; Laschi, Marcella; Millucci, Lia; Amato, Loredana; Tinti, Laura; Serchi, Tommaso; Chellini, Federico; Spreafico, Adriano; Santucci, Annalisa
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This article is from Journal of Cellular Physiology , volume 227 . Abstract Alkaptonuria (AKU) is a rare genetic disease associated with the accumulation of homogentisic acid (HGA) and its oxidized/polymerized products which leads to the deposition of melanin-like pigments (ochronosis) in connective tissues. Although numerous case reports have described ochronosis in joints, little is known on the molecular mechanisms leading to such a phenomenon. For this reason, we characterized biochemically...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427902
PubMed Central
by Oh, Seung-June; Son, Hwancheol; Kim, Soo Wong; Lee, Kyu-Sung; Choo, Myung-Soo; Kim, Seon-Ok; Lee, Moo Song
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This article is from International Neurourology Journal , volume 16 . Abstract Purpose: Psychometric properties of the overactive bladder questionnaire (OAB-q) were recently examined. However, since the cross-cultural adaptation of a non-English version of the OAB-q has never been demonstrated, we evaluated the psychometric properties of a Korean version of the OAB-q in a Korean population with OAB. Methods: A prospective cohort study involving 116 women with 58 OAB and 58 control subjects was...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395803
PubMed Central
by Jha, Rakhi K.; Jha, Pradeep K.; Chaudhury, Koel; Rana, Suresh V.S.; Guha, Sujoy K.
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This article is from Nano Reviews , volume 5 . Abstract Among the various applications of nano-biotechnology, healthcare is considered one of the most significant domains. For that possibility to synthesize various kind of nanoparticles (NPs) and the ever-increasing ability to control their size as well as structure, to improve surface characteristics and binding NPs with other desired curing agents has played an important role. In this paper, a brief sketch of various kinds of nanomaterials...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943174
PubMed Central
by Serrato, Rodrigo V.
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This article is from Frontiers in Cellular and Infection Microbiology , volume 4 . Abstract Biological nitrogen fixation (BNF) is a process in which the atmospheric nitrogen (N2) is transformed into ammonia (NH3) by a select group of nitrogen-fixing organisms, or diazotrophic bacteria. In order to furnish the biologically useful nitrogen to plants, these bacteria must be in constant molecular communication with their host plants. Some of these molecular plant-microbe interactions are very...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153317
PubMed Central
by Wang, Jingzhou; Garcia-Bailo, Bibiana; Nielsen, Daiva E.; El-Sohemy, Ahmed
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This article is from PLoS ONE , volume 9 . Abstract Background: The ‘Blood-Type’ diet advises individuals to eat according to their ABO blood group to improve their health and decrease risk of chronic diseases such as cardiovascular disease. However, the association between blood type-based dietary patterns and health outcomes has not been examined. The objective of this study was to determine the association between ‘blood-type’ diets and biomarkers of cardiometabolic health and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893150
PubMed Central
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This article is from International Journal of Fertility & Sterility , volume 8 . Abstract Premature ovarian failure (POF) is identified as a heterogeneous disorder leading to amenorrhea and ovarian failure before the age of 40 years. The first known symptom of the disease is having irregular menstrual periods. The phenotype appearance of POF depends significantly on the variations in hormones. Low levels of gonadal hormones (estrogens and inhibins) and increased level of gonadotropins...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973172
PubMed Central
by Ellis, Ronald; Riedmann, Eva M
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This article is from Human Vaccines & Immunotherapeutics , volume 9 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981833
PubMed Central
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This article is from Acta Crystallographica Section E: Structure Reports Online , volume 68 . Abstract In the title complex, [Zn(C10H8N5)Cl]n, the ZnII ion is four-coordinated by one Cl atom and three N atoms from two in situ-generated deprotonated 5-(1-methyl-1H-benzimidazol-2-yl-κN3)-1,2,3-triazol-1-ide ligands in a slightly distorted tetra­hedral geometry. The ZnII ions are bridged by the ligands, forming a helical chain along [001]. C—H⋯N and C—H⋯Cl hydrogen bonds and π–π...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343902
PubMed Central
by Yu, Jung-Hee; Lee, Kyu-Beck; Lee, Jae Eun; Kim, Hyang; Kim, Kyungeun; Jang, Ki-Seok; Park, Moon Hyang
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This article is from Journal of Korean Medical Science , volume 27 . Abstract Henoch-Schönlein purpura (HSP) is common in childhood and often self-limiting. There have been limited studies on elderly-onset HSP nephritis (HSPN). A 76-yr-old man was transferred to our hospital with a 1-month history of oliguria, abdominal pain, edema and palpable purpura in the legs. Three months ago, he was admitted to another hospital with jaundice, and consequently diagnosed with early common bile duct...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410247
PubMed Central
by Ianiri, Giuseppe; Abhyankar, Ritika; Kihara, Akio; Idnurm, Alexander
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This article is from PLoS ONE , volume 9 . Abstract The production and dissemination of spores by members of the fungal kingdom is a major reason for the success of this eukaryotic lineage in colonizing most terrestrial ecosystems. Ballistospores are a type of spore produced by basidiomycete fungi, such as the mushrooms and plant pathogenic rusts. These spores are forcefully discharged through a unique liquid-drop fusion mechanism, enabling the aerosolization of these particles that can...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141788
PubMed Central
by Zhang, Wei; Du, Jiang-Yuan; Jiang, Zedong; Okimura, Takasi; Oda, Tatsuya; Yu, Qing; Jin, Jun-O
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This article is from Marine Drugs , volume 12 . Abstract Marine-derived sulfated polysaccharides have been shown to possess certain anti-virus, anti-tumor, anti-inflammatory and anti-coagulant activities. However, the in vivo immunomodulatory effects of marine-derived pure compounds have been less well characterized. In this study, we investigated the effect of ascophyllan, a sulfated polysaccharide purified from Ascophyllum nodosum, on the maturation of mouse dendritic cells (DCs) in vitro and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113820
PubMed Central
by Kutz, A; Grolimund, E; Mueller, B; Schuetz, P
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This article is from Critical Care , volume 18 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068382
PubMed Central
by Matthias, Christoph
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This article is from GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery , volume 6 . Abstract The following article presents nasal septum and turbinate surgery. First an overview with special consideration of the anatomical and physiological background is given followed by indications for surgical procedures. Key steps of the gold standard procedure first described by Cottle and common variations are presented. Furthermore, some techniques dealing with special problems of the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199838
PubMed Central
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This article is from Implementation Science : IS , volume 9 . Abstract Background: Health services are subject to frequent changes, yet there has been insufficient research to address how staff working within these services perceive the climate for implementation. Staff perceptions, particularly of barriers to change, may affect successful implementation and the resultant quality of care. This study measures staff perceptions of barriers to change in acute mental healthcare. We identify whether...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016533
PubMed Central
by Chang, Eddie L.; Simmers, Christa; Knight, D. Andrew
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This article is from Pharmaceuticals , volume 3 . Abstract Metal ion complexes are playing an increasing role in the development of antimicrobials. We review here the antimicrobial properties of cobalt coordination complexes in oxidation state 3+. In addition to reviewing the cobalt complexes containing polydentate donor ligands, we also focus on the antimicrobial activity of the homoleptic [Co(NH3)6]3+ ion.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033948
This article is from Critical Care , volume 18 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068651
PubMed Central
by Casadevall, Arturo
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This article is from mBio , volume 5 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128361
PubMed Central
by Lee, Byeong Ha; Kim, Young Ho; Park, Kwan Seob; Eom, Joo Beom; Kim, Myoung Jin; Rho, Byung Sup; Choi, Hae Young
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This article is from Sensors (Basel, Switzerland) , volume 12 . Abstract Fiber optic interferometers to sense various physical parameters including temperature, strain, pressure, and refractive index have been widely investigated. They can be categorized into four types: Fabry-Perot, Mach-Zehnder, Michelson, and Sagnac. In this paper, each type of interferometric sensor is reviewed in terms of operating principles, fabrication methods, and application fields. Some specific examples of recently...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376629
PubMed Central
by Regenbrecht, Carolin; Waldvogel, Siegfried R
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This article is from Beilstein Journal of Organic Chemistry , volume 8 . Abstract 2,3,6,7,10,11-Hexahydroxytriphenylene of good quality and purity can be obtained via anodic treatment of catechol ketals and subsequent acidic hydrolysis. The electrolysis is conducted in propylene carbonate circumventing toxic and expensive acetonitrile. The protocol is simple to perform and superior to other chemical or electrochemical methods. The key of the method is based on the low solubility of the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511005
PubMed Central
by Perdomo, Doranda; Baron, Bruno; Rojo-Dominguez, Arturo; Raynal, Bertrand; England, Patrick; Guillen, Nancy
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This article is from Scientific Reports , volume 3 . Abstract The lysine and glutamic acid rich protein KERP1 is a unique surface adhesion factor associated with virulence in the human pathogen Entamoeba histolytica. Both the function and structure of this protein remain unknown to this date. Here, we used circular dichroism, analytical ultracentrifugation and bioinformatics modeling to characterize the structure of KERP1. Our findings revealed that it is an α-helical rich protein organized as...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558696
PubMed Central
by Jensen, Mads Radmer; Simonsen, Lene; Lonsdale, Markus; Bulow, Jens Bj?rn
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This article is from EJNMMI Research , volume 3 . Abstract Background: In mice, 18F-fluorodeoxyglucose (18F-FDG) positron-emission tomography/computed tomography (PET/CT) lymphography enables detailed imaging of the lymphatic system and quantification of lymph node function. If this applies to humans, it may improve staging of several malignancies. The aim of this study was to elucidate whether foot skin depots of 18F-FDG make PET/CT imaging of the lower extremity lymphatic system possible in...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610292
PubMed Central
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This article is from BMC Ecology , volume 13 . Abstract Background: Rising temperatures and other environmental factors influenced by global climate change can cause increased physiological stress for many species and lead to range shifts or regional population extinctions. To advance the understanding of species’ response to change and establish links between individual and ecosystem adaptations, physiological reactions have to be compared between populations living in different...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663710
PubMed Central
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This article is from Parasites & Vectors , volume 7 . Abstract Background: Toxoplasma gondii is an obligate intracellular parasite that causes a pathological status known as toxoplasmosis, which has a huge impact on human and animal health. Currently, the main control strategy depends on the usage of drugs that target the acute stage of the infection, however, drawbacks were encountered while applying this method; therefore, development of an alternative effective method would be important...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164750
PubMed Central
by Matatagui, Daniel; Fontecha, Jose Luis; Fernandez, Maria Jesus; Gracia, Isabel; Cane, Carles; Santos, Jose Pedro; Horrillo, Maria Carmen
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This article is from Sensors (Basel, Switzerland) , volume 14 . Abstract The following paper examines a time-efficient method for detecting biological warfare agents (BWAs). The method is based on a system of a Love-wave immunosensor combined with a microfluidic chip which detects BWA samples in a dynamic mode. In this way a continuous flow-through of the sample is created, promoting the reaction between antigen and antibody and allowing a fast detection of the BWAs. In order to prove this...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168433
PubMed Central
by Ohnishi, Takashi; Sakiyama, Yojiro; Okuri, Yuichi; Kimura, Yuji; Sugiyama, Nami; Saito, Takayuki; Takahashi, Masayoshi; Kobayashi, Takumi
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This article is from Current Alzheimer Research , volume 11 . Abstract The prediction of efficacy in long-term treatment of acetylcholinesterase inhibitors (AChEIs) is a major clinical issue, although no consistently strong predictive factors have emerged thus far. The present analyses aimed to identify factors for predicting long-term outcome of galantamine treatment. Analyses were conducted with data from a 24 weeks randomized, double-blind, placebo controlled trial to evaluate the efficacy...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979115
PubMed Central
by Stevanovic, Darko M.; Grefhorst, Aldo; Themmen, Axel P. N.; Popovic, Vera; Holstege, Joan; Haasdijk, Elize; Trajkovic, Vladimir; van der Lely, Aart-Jan; Delhanty, Patric J. D.
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This article is from PLoS ONE , volume 9 . Abstract Ghrelin, the endogenous growth hormone secretagogue, has an important role in metabolic homeostasis. It exists in two major molecular forms: acylated (AG) and unacylated (UAG). Many studies suggest different roles for these two forms of ghrelin in energy balance regulation. In the present study, we compared the effects of acute intracerebroventricular administration of AG, UAG and their combination (AG+UAG) to young adult Wistar rats on food...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031147
PubMed Central
by Yamamoto, Takanobu; Byun, Jaemin; Zhai, Peiyong; Ikeda, Yoshiyuki; Oka, Shinichi; Sadoshima, Junichi
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This article is from PLoS ONE , volume 9 . Abstract Nicotinamide phosphoribosyltransferase (Nampt), the rate-limiting enzyme for nicotinamide adenine dinucleotide (NAD+) synthesis, and Sirt1, an NAD+-dependent histone deacetylase, protect the heart against ischemia/reperfusion (I/R). It remains unknown whether Nampt mediates the protective effect of ischemic preconditioning (IPC), whether nicotinamide mononucleotide (NMN, 500 mg/kg), a product of Nampt in the NAD+ salvage pathway, mimics the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048236
PubMed Central
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This article is from PLoS ONE , volume 9 . Abstract In Arabidopsis, the regulation network of the seed maturation program controls the induction of seed dormancy. Wheat EST sequences showing homology with the master regulators of seed maturation, LEAFY COTYLEDON1 (LEC1), LEC2 and FUSCA3 (FUS3), were searched from databases and designated respectively as TaL1L (LEC1-LIKE), TaL2L (LEC2-LIKE), and TaFUS3. TaL1LA, TaL2LA and TaFUS3 mainly expressed in seeds or embryos, with the expression limited...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161473
PubMed Central
by Marrone, April K; Kucherenko, Mariya M; Rishko, Valentyna M; Shcherbata, Halyna R
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This article is from BMC Neuroscience , volume 12 . Abstract Background: The Dystrophin Glycoprotein Complex (DGC) is a large multi-component complex that is well known for its function in muscle tissue. When the main components of the DGC, Dystrophin (Dys) and Dystroglycan (Dg) are affected cognitive impairment and mental retardation in addition to muscle degeneration can occur. Previously we performed an array of genetic screens using a Drosophila model for muscular dystrophy in order to find...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217851
PubMed Central
by Zhang, Jisong; He, Jian; Xia, Jingwen; Chen, Zhen; Chen, Xiaodong
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This article is from Diagnostic Pathology , volume 7 . Abstract Background: Delayed neutrophil apoptosis may be an important factor in the persistent inflammation associated with chronic obstructive pulmonary disease (COPD). Bcl-2 family proteins are important regulators of neutrophil apoptosis. We determined the mRNA levels of pro-apoptotic Bak and anti-aptototic Bcl-xl and Mcl-1 members of the Bcl-2 family in unstimulated peripheral blood neutrophils from patients with mild to moderate COPD...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488503
PubMed Central
by Agresta, Ferdinando; Ansaloni, Luca; Catena, Fausto; Verza, Luca Andrea; Prando, Daniela
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This article is from World Journal of Emergency Surgery : WJES , volume 9 . Abstract Appendectomy is one of the most frequently performed operative procedures in general surgery departments of every size and category. Laparoscopic Appendectomy – LA - as compared to Open Appendectomy – OA - was very controversial at first but has found increasing acceptance all over the World, although the percentage of its acceptance is different in the various single National setting. Various meta-analyses...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984433
PubMed Central
by Opalka, Suzanne M; Longstreet, Ashley R; McQuade, D Tyler
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This article is from Beilstein Journal of Organic Chemistry , volume 7 . Abstract Herein, we demonstrate that a homogeneous catalyst can be prepared continuously via reaction with a packed-bed of a catalyst precursor. Specifically, we perform continuous proline catalyzed α-aminoxylations using a packed-bed of L-proline. The system relies on a multistep sequence in which an aldehyde and thiourea additive are passed through a column of solid proline, presumably forming a soluble oxazolidinone...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252872
PubMed Central
by Harold, Simon
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This article is from BMC Plant Biology , volume 13 . Abstract Contributing reviewers: The editors of BMC Plant Biology would like to thank all of our reviewers who have contributed to the journal in Volume 12 (2012).
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576327
PubMed Central
by Ehsani, Maryam; Amin Marashi, Mahmood; Zabihi, Ebrahim; Issazadeh, Maryam; Khafri, Soraya
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This article is from International Journal of Molecular and Cellular Medicine , volume 2 . Abstract Removing the bacteria, including Enterococcus faecalis, from the root canal is one of the important aims in endodontic treatment.We aimed to compare the antibacterial activity of Chlorhexidine with two natural drugs. The antibacterial activities of three different propolis extracts (alcohol concentrations: 0, 15, 40%) and Aloe vera gel on E. faecalis were compared using three methods: disk...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920536
This article is from BMC Research Notes , volume 7 . Abstract Background: The HELLP syndrome (haemolysis, elevated liver enzymes, and low-platelet count) occurs in about 0.5 to 0.9% of all pregnancies. With occurrence of thrombocytopaenia, it signals for several potentially lethal conditions such as complete or partial HELLP syndrome, thrombotic thrombocytopaenic purpura and acute fatty liver of pregnancy. Case presentation: A previously healthy 27-year-old, Sinhala ethnic primigravida with...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083337
PubMed Central
by Fakharian, Atefeh; Hamidi, Nima; Hosseinloo, Behnam Haji; Rezaei, Samira; Afshar, Elnaz Ehteshami; Sharif-Kashani, Babak; Behzadnia, Neda; Karam, Mehrdad Bakhshayesh; Gachkar, Latif; Emami, Habib
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This article is from Tanaffos , volume 10 . Abstract Background: Pulmonary hypertension (PH) is a significant cause of morbidity and mortality in patients suffering from pulmonary parenchymal diseases. Diagnosis of PH has always been a major clinical dilemma due to its non-specific clinical manifestations. However, diagnosing PH and determining its severity are essential for the prognosis and treatment planning in PH patients. This study aimed at evaluating the correlation between the pulmonary...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153157
PubMed Central
by Burke, Tomas R.; Tsang, Stephen H.; Zernant, Jana; Smith, R. Theodore; Allikmets, Rando
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This article is from Molecular Vision , volume 18 . Abstract Purpose: To report genetic and phenotypic discordance across two generations of a family with autosomal recessive Stargardt disease (STGD1) and to compare pathogenicities of the G1961E and A1038V alleles of the ATP-binding cassette transporter, subfamily A, member 4 (ABCA4) gene. Methods: Five members of a family with STGD1 (patients 1–4, affected; patient 5, carrier) were included. Clinical assessment was performed together with...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272278
PubMed Central
by Kalampokis, Ioannis; Yoshizaki, Ayumi; Tedder, Thomas F
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This article is from Arthritis Research & Therapy , volume 15 . Abstract B cell abnormalities contribute to the development and progress of autoimmune disease. Traditionally, the role of B cells in autoimmune disease was thought to be predominantly limited to the production of autoantibodies. Nevertheless, in addition to autoantibody production, B cells have other functions potentially relevant to autoimmunity. Such functions include antigen presentation to and activation of T cells,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624502
PubMed Central
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This article is from Frontiers in Genetics , volume 5 . Abstract Fetal alcohol spectrum disorders (FASD) are a group of related conditions that arise from prenatal exposure to maternal consumption of the teratogen, ethanol. It has been estimated that roughly 1% of children in the US suffer from FASD (Sampson etal., 1997), though in some world populations, such as inhabitants of some poorer regions of South Africa, the rate can climb to as high as 20% (May etal., 2013). FASD are the largest...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040491
PubMed Central
by Suzuki, Junji; Kanemaru, Kazunori; Ishii, Kuniaki; Ohkura, Masamichi; Okubo, Yohei; Iino, Masamitsu
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This article is from Nature Communications , volume 5 . Abstract The endoplasmic reticulum (ER) and mitochondria accumulate Ca2+ within their lumens to regulate numerous cell functions. However, determining the dynamics of intraorganellar Ca2+ has proven to be difficult. Here we describe a family of genetically encoded Ca2+ indicators, named calcium-measuring organelle-entrapped protein indicators (CEPIA), which can be utilized for intraorganellar Ca2+ imaging. CEPIA, which emit green, red or...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082642